Cyclopentane-modified PNA improves the sensitivity of nanoparticle-based scanometric DNA detection.

نویسندگان

  • Jonathan K Pokorski
  • Jwa-Min Nam
  • Rafael A Vega
  • Chad A Mirkin
  • Daniel H Appella
چکیده

trans-Cyclopentane-modified PNA has been successfully utilized as a target capture strand to improve the detection limit of a known DNA detection assay, and provide high levels of mismatch discrimination.

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عنوان ژورنال:
  • Chemical communications

دوره 16  شماره 

صفحات  -

تاریخ انتشار 2005